Chemical pathology

The department of chemical pathology and metabolism has laboratories based at Epsom Hospital and St Helier Hospital offering a diagnostic and advisory service to the local and wider health economy.

The department provides a comprehensive range of routine analyses, a number of which are available on a full 24-hour service, together with a range of more specialised analyses.

Specialised analytical services

We provide a range of specialised analyses in the areas of reproductive and adrenal hormones, PTH, a range of vitamins, tumour markers, biogenic amines, and therapeutic drug monitoring.  

These are undertaken for the local population and as a tertiary provider of services for other laboratories across the UK.

Urgent tests

Many tests can be performed urgently but these must be discussed in advance.

Clinical advice

Experienced clinicians and scientists are available to discuss the use and interpretation of specialised tests.

Laboratory reference ranges

To view the latest laboratory reference ranges, please read this document:  Laboratory reference ranges [pdf].

Regional newborn bloodspot screening service

The department also includes the South West Thames Newborn Bloodspot Screening laboratory.  This provides screening for rare congenital, usually inherited, disorders using a bloodspot sample. The laboratory follows guidelines produced by the UK Newborn Screening Programme Centre.  For more infomation contact the newborn blood spot website (opens in a new window).

Clinical services

Clinicians from the department operate clinics at St Helier and Epsom hospitals for management of lipid disorders and renal stones.

Research

The department has close links with the research and clinical trials units within the hospital and a significant record of published works on many aspects of metabolism, analysis and investigation of disease.

Teaching

Senior members of staff are involved in training and education of postgraduate and undergraduate students both within the trust and in academic units in the south east. 

Location and opening hours

St Helier Hospital: first and third floors, D block
Monday - Friday from 8am - 5.30pm and Saturdays from 9am - 12.30pm

Epsom Hospital: first floor, Headley Wing
Monday - Friday from 9am - 5.30pm and Saturdays from 9am - 12.30pm

Emergency cover is maintained at all other times, including 'on call' consultant cover. 'On call' staff may be contacted by calling 020 8296 2000 (St Helier) or 01372 735735 (Epsom). 

Contact details

St Helier laboratory enquiries

Tel: 020 8296 2825
Fax: 020 8641 2633
Email: Est-tr.chempathESTH@nhs.net

For direct clinical and specialist assay queries you can call our duty biochemist on 07975 232440. 

This will be answered during normal working hours by one of the senior medical or scientific staff in the laboratory. 

Epsom laboratory enquiries

Tel: 01372 735258
Fax: 01372 735498
Email: Est-tr.chempathESTH@nhs.net

Key staff

Clinical

Dr Nikhil Johri, Consultant
Tel: 020 8296 2660
Email: nikhil.johri@nhs.net

Dr Mehdi Mirzazadeh, Consultant
Tel: 020 8296 2661
Email: medhi.mirzazadeh@nhs.net

Dr Rashim Salota, Consultant
Tel: 020 8296 2432
Email: rashimsalota@nhs.net

Helen Johnstone, Consultant Clinical Scientist
Tel: 020 8296 2658
Email: h.johnstone@nhs.net

Specialist registrar
Tel: 020 8296 2658

Scientific and Technical

Asam Saeed, Service Manager – Blood Sciences
Tel: 020 8296 2804 (St Helier) or 01372 735735 ext 6105 (Epsom)
Email: asam.saeed@nhs.net

Tom Walton, Chemistry Automation Lead Scientist
Tel: 020 8296 3360 (St Helier) or 01372 735735 ext 6105 (Epsom)
Email: thomas.walton1@nhs.net

Hitesh Gokani, Specialist Services Lead Scientist
Tel: 020 8296 3360
Email: h.gokani@nhs.net

Rachelle Garstone, Lead Scientist – South West Thames Newborn Screening Laboratory
Tel: 020 8296 2991
Email: rachelle.garstone@nhs.net

 

Troponin

A Troponin value of greater than 40 ng/L suggests evolving acute myocardial infarction (AMI).

To exclude acute cardiac damage, serial samples are required. A further rise suggests AMI. A rise to a value exceeding 100 ng/L is highly suggestive of AMI.

A Troponin I value that remains stable suggests cardiac damage secondary to another pathophysiology. A diagnosis of AMI requires a change in troponin values in the appropriate clinical context.

A Troponin value of less than 40 ng/L indicates that no cardiac damage is detected.

To exclude acute cardiac damage serial samples are required. If all samples remain <40 ng/L acute myocardial infarction is excluded.

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